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Publications Update

Publications Update # 90

How to give great presentations, censoring in clinical trials causing bias, molecular classification in fertility-sparing treatment of endometrial cancer, ARIEL 4 final OS data, guidelines for using checkpoint inhibitors in older patients

Publications Update # 89

Implications of the Present Perfect Tense, PARP inhibitors and recent withdrawals, retroperitoneal debulking video, ovarian cancer guidelines by ASCO and some GYOEDU updates

Publications Update # 88

Confessions of a recovering people pleaser, deep-dive into the management of non-myoinvasive uterine papillary serous carcinoma

Publications Update # 87

Publications Update # 86

New Year Resolutions, A Practical Approach to Molecular Classification of Endometrial Cancer, Cervical Cancer Review article, management of Cancer Cachexia and the Changing Practice of Gynecology Oncology.

Publications Update # 85

New year resolutions, ENSURE and TOTEM trial with GOG 0258 long-term survival, and modified techniques for laparoscopic radical hysterectomy.

Publications Update # 84

Yo-Yo Ma at the reopening of the Notre Dame, CDK 4/6 inhibitors in endometrial cancer, real-world analysis of folate testing in endometrial cancer, and the inaugural episode of GYOEDU Podcast.

PALEO Trial: Palbociclib + Letrozole in Endometrial Cancer

The combination of palbociclib and letrozole significantly improved PFS compared to placebo with letrozole. However, it was associated with higher hematologic toxicities, particularly neutropenia.

Publications Update # 83

A trick to powerful speaking, LEAP-001 Study: Pembro/Lenvima vs. Carbo/Taxol in EndoCa, Opportunistic Salpingectomy.

LEAP-001: Pembro/Lenvima vs. Carbo/Taxol in Advanced/Recurrent Endometrial Cancer

First-line lenvatinib plus pembrolizumab did not significantly improve PFS or OS compared to chemotherapy in mismatch repair-proficient (pMMR) advanced endometrial cancer. Toxicity was higher in the experimental arm but manageable. dMMR exploratory analysis shows promise in this subgroup.