Publications Update # 84
Yo-Yo Ma at the reopening of the Notre Dame, CDK 4/6 inhibitors in endometrial cancer, real-world analysis of folate testing in endometrial cancer, and the inaugural episode of GYOEDU Podcast.
Publications Update
PALEO Trial: Palbociclib + Letrozole in Endometrial Cancer
The combination of palbociclib and letrozole significantly improved PFS compared to placebo with letrozole. However, it was associated with higher hematologic toxicities, particularly neutropenia.
Publications Update # 83
A trick to powerful speaking, LEAP-001 Study: Pembro/Lenvima vs. Carbo/Taxol in EndoCa, Opportunistic Salpingectomy.
LEAP-001: Pembro/Lenvima vs. Carbo/Taxol in Advanced/Recurrent Endometrial Cancer
First-line lenvatinib plus pembrolizumab did not significantly improve PFS or OS compared to chemotherapy in mismatch repair-proficient (pMMR) advanced endometrial cancer. Toxicity was higher in the experimental arm but manageable.
dMMR exploratory analysis shows promise in this subgroup.
Publications Update # 82
Book recommendation - Get It Done by Ayelet Fishbach, MITO-18 trial summary and discussion points, NEJM paper - BALANCE trial, Trial flashback - road to carboplatin and taxol video (5 mins)
Publications Update # 81
Video summary of CHIPOR trial, study summary of CHIPOR trial
Publications Update # 80
Finding time to exercise, Management of STIC, NADINA trial in advanced melanoma, Final OS Keynote A-18, and overtreatment of locally advanced cervical cancer treatment prior to OUTBACK publication
Publications Update # 79
Strategies to overcome workaholism, prevent surgical site infections, and conduct the STOP-IT trial and BALANCE trial to reduce antibiotic duration.
Publications Update # 78
Medicine is Difficult article, discussion of interlace trial and PRIMA final survival data
Publications Update # 77
Living Room - Podcast Episode from Love+Radio, Keynote B21 trial and a video discussion of the trial and Compassion 16 trial in cervical cancer